TSCA Significant New Use Rules (SNURs)

Current understanding

Under Section 5(a)(2) of the Toxic Substances Control Act, EPA issues Significant New Use Rules (SNURs) requiring manufacturers and processors to submit a Significant New Use Notice at least 90 days before manufacturing or processing designated chemical substances for a new use. SNURs are commonly paired with premanufacture notice (PMN) review outcomes and existing TSCA Section 5(e) consent orders, giving EPA an opportunity to evaluate and, if warranted, restrict new uses before market entry. Practical effects include compliance costs for notifiers, delays to commercialization, and health/environmental screening of novel exposure pathways.

Evidence log

• 2026-08-26 — Significant New Use Rules on Certain Chemical Substances (24-5.5e): 2026 — Significant New Use Rules on Certain Chemical Substances (24-5.5e) (citation removed): Additional SNUR package finalized requiring 90-day pre-manufacture/import/processing notice for designated new uses of certain already-reviewed chemicals, with EPA review-and-act gate before commencement. (novelty: 2) (novelty: 2)
• 2026-07-23 — Significant New Use Rules on Certain Chemical Substances (26-3): EPA proposed a SNUR package (26-3) covering multiple PMN chemical substances already subject to TSCA Section 5(e) Orders, requiring 90-day advance notification before manufacture or processing for designated significant new uses. (novelty: 2)
• 2026-07-24 — Significant New Use Rule on a Certain Chemical Substance; Multi-Walled Carbon Nanotubes: Multi-walled carbon nanotubes added to the roster of TSCA SNURs, extending the 90-day pre-manufacture/pre-processing notification regime to this nanomaterial class. (novelty: 2)

Open questions

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